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The Paradigm of Targeting an Oncogenic Tyrosine Kinase: Lesson from BCR-ABL  | IntechOpen
The Paradigm of Targeting an Oncogenic Tyrosine Kinase: Lesson from BCR-ABL | IntechOpen

Targeting the SH2-Kinase Interface in Bcr-Abl Inhibits Leukemogenesis: Cell
Targeting the SH2-Kinase Interface in Bcr-Abl Inhibits Leukemogenesis: Cell

A model for the regulation of BCR-ABL nuclear import through conformational  interplay between the kinase domain, the FABD and the NLS region.
A model for the regulation of BCR-ABL nuclear import through conformational interplay between the kinase domain, the FABD and the NLS region.

Flying under the radar: the new wave of BCR–ABL inhibitors | Nature Reviews  Drug Discovery
Flying under the radar: the new wave of BCR–ABL inhibitors | Nature Reviews Drug Discovery

STI571: an inhibitor of the BCR-ABL tyrosine kinase for the treatment of  chronic myelogenous leukaemia - The Lancet Oncology
STI571: an inhibitor of the BCR-ABL tyrosine kinase for the treatment of chronic myelogenous leukaemia - The Lancet Oncology

Disabling Abl—Perspectives on Abl kinase regulation and cancer  therapeutics: Cancer Cell
Disabling Abl—Perspectives on Abl kinase regulation and cancer therapeutics: Cancer Cell

The tyrosine kinase c-Abl potentiates interferon-mediated antiviral  immunity by STAT1 phosphorylation - ScienceDirect
The tyrosine kinase c-Abl potentiates interferon-mediated antiviral immunity by STAT1 phosphorylation - ScienceDirect

Figure 1 from STI571: targeting BCR-ABL as therapy for CML. | Semantic  Scholar
Figure 1 from STI571: targeting BCR-ABL as therapy for CML. | Semantic Scholar

Allosteric Inhibition of Bcr-Abl Kinase by High Affinity Monobody  Inhibitors Directed to the Src Homology 2 (SH2)-Kinase Interface* - Journal  of Biological Chemistry
Allosteric Inhibition of Bcr-Abl Kinase by High Affinity Monobody Inhibitors Directed to the Src Homology 2 (SH2)-Kinase Interface* - Journal of Biological Chemistry

Tyrosine-kinase inhibition in treatment of chronic myeloid leukaemia - The  Lancet
Tyrosine-kinase inhibition in treatment of chronic myeloid leukaemia - The Lancet

BCR-ABL1 and the Philadelphia chromosome - Part 3: The BCR-ABL fusion  protein - YouTube
BCR-ABL1 and the Philadelphia chromosome - Part 3: The BCR-ABL fusion protein - YouTube

Targeting the BCR-ABL Tyrosine Kinase in Chronic Myeloid Leukemia | NEJM
Targeting the BCR-ABL Tyrosine Kinase in Chronic Myeloid Leukemia | NEJM

Bcr-Abl and Imatinib (STI571 or Gleevec) - Proteopedia, life in 3D
Bcr-Abl and Imatinib (STI571 or Gleevec) - Proteopedia, life in 3D

Bcr-Abl阻害 | Bcr-Abl Inhibition
Bcr-Abl阻害 | Bcr-Abl Inhibition

Mechanism of action of BCR (breakpoint cluster region)-ABL (Abelson 1... |  Download Scientific Diagram
Mechanism of action of BCR (breakpoint cluster region)-ABL (Abelson 1... | Download Scientific Diagram

Imatinib resistance in chronic myeloid leukaemia caused by Bcr-Abl kinase  domain and non-Bcr-Abl mutations: a comparison and review. - Australian  Medical Student Journal
Imatinib resistance in chronic myeloid leukaemia caused by Bcr-Abl kinase domain and non-Bcr-Abl mutations: a comparison and review. - Australian Medical Student Journal

Hematology Reports | Free Full-Text | Outcomes of the Pregnancies with  Chronic Myeloid Leukemia in the Tyrosine Kinase Inhibitor Era and  Literature Review
Hematology Reports | Free Full-Text | Outcomes of the Pregnancies with Chronic Myeloid Leukemia in the Tyrosine Kinase Inhibitor Era and Literature Review

Schematic representation of the mechanism of action of the BCR-ABLTKIs....  | Download Scientific Diagram
Schematic representation of the mechanism of action of the BCR-ABLTKIs.... | Download Scientific Diagram

Regulation of the c-Abl and Bcr–Abl tyrosine kinases | Nature Reviews  Molecular Cell Biology
Regulation of the c-Abl and Bcr–Abl tyrosine kinases | Nature Reviews Molecular Cell Biology

Frontiers | The Discovery of Novel BCR-ABL Tyrosine Kinase Inhibitors Using  a Pharmacophore Modeling and Virtual Screening Approach
Frontiers | The Discovery of Novel BCR-ABL Tyrosine Kinase Inhibitors Using a Pharmacophore Modeling and Virtual Screening Approach

Mechanism of Action of BCR-ABL and of Its Inhibition by Imatinib. Panel...  | Download Scientific Diagram
Mechanism of Action of BCR-ABL and of Its Inhibition by Imatinib. Panel... | Download Scientific Diagram

BCR-ABL activates multiple downstream signaling pathways that... | Download  Scientific Diagram
BCR-ABL activates multiple downstream signaling pathways that... | Download Scientific Diagram

Structure and Dynamic Regulation of Abl Kinases* - ScienceDirect
Structure and Dynamic Regulation of Abl Kinases* - ScienceDirect

Second generation inhibitors of BCR-ABL for the treatment of  imatinib-resistant chronic myeloid leukaemia | Nature Reviews Cancer
Second generation inhibitors of BCR-ABL for the treatment of imatinib-resistant chronic myeloid leukaemia | Nature Reviews Cancer

IJMS | Free Full-Text | The Role of Mitochondrial DNA Damage and Repair in  the Resistance of BCR/ABL-Expressing Cells to Tyrosine Kinase Inhibitors
IJMS | Free Full-Text | The Role of Mitochondrial DNA Damage and Repair in the Resistance of BCR/ABL-Expressing Cells to Tyrosine Kinase Inhibitors